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xxiii LIST OF CONTRIBUTORS. 1 Determination of phase identity The United States Pharmacopeia contains a general chapter on x-ray diffraction , damaged by transgenics, 293 discovery of XX-XY sex determination Knudson, Alfred (retinoblastoma studies), 212 L lab equipment, 14 lab technicians, career of, 1516 laboratories, 1315 lagging strands, 108 large offspring syndrome (LOS), 307308 law of independent assortment, 45 laws of inheritance, 37 leading strands, 108 lentiviruses, gene therapy and, 239240 lethal alleles, 56 lethal phenotypes, 56 leukemias, 206 ligase, 104, 109, 347 Lincoln, President Abraham, genetic testing and, 317 linkage, 347 linkage analysis, 5962, 241 location-dependent sex determination, 71 loci chromosome, 26 defined, 347 DNA fingerprinting and, 267268 multiple with multiple alleles, 5456 phenotypes and, 40 LOS (large offspring syndrome), 307308 loss-of-function mutations, 199, 211 lung cancer, 217218 lymphomas, 206 M MacLeod, Colin (transforming principle studies), 328 macrophage, 254 mad cow disease, 157 maize, mutations of, 285 malignancies, 205206 mapping gene, 240242, 245246 gene pools, 260263 Marfan syndrome, 179 marker gene, transgenics and, 289 markers, DNA fingerprinting and, 267268 in, 66 sex determination of, Forex in Yecapixtla transgenics and, 297 X-linked traits in, 7677 insertion defined, 347 mutations, 190, 193, 197, 199 insulator genes, managing transcrip- tion, 149 intelligence, heritability of, 314315 intercalating agent, inducing mutations, 196197 interkinesis, of meiosis, 34 interphase of cell cycle, 2728 defined, 347 replication in, 101 introgression, concerns about, 292293 introns defined, 125, 347 removing, 127128, 153 inversion, 233, 234 Irons, Dr.
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